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Comparison of NovaMin and other Calcium Phosphate Technologies

Comparison of NovaMin and other Calcium Phosphate Technologies

Home > Competitive Calcium Phosphate Technologies

Competitive Calcium Phosphate Technologies

A Review

November 1, 2005

Purpose: The purpose of this review is to establish a better understanding of competitive remineralization technologies that are currently competing with NovaMin in the professional dental market place.  Although the focus of these competitive technologies is tooth remineralization, we will focus on the desensitization potential of these technologies as compared to the NovaMin containing products currently being marketed for sensitivity reduction.

Background:  Over the past seven years the interest in calcium phosphate based remineralization technologies has grown significantly and a number of new technologies are currently available in the professional dental products arena.  These technologies are relatively new and are not well understood by most clinicians and hygienists and there is confusion about the similarities and differences between technologies.  The following summary will establish the differences between NovaMin and other currently available technologies to help gain a better understanding of the competitive advantages of NovaMin.

Current Calcium Phosphate Technologies:  Currently there are three technologies that are present in the market place that claim to offer remineralization and related benefits to the end user.  These technologies include Recaldent (found in GC America's MI paste and Trident Chewing gum), Amorphous Calcium Phosphate or ACP (found in Church and Dwight's Enamel Care Toothpaste) SensiStat (found in Ortek's Proclude and Denclude products) and Restore Toothpaste.

FAQs NovaMin Recaldent SensiStat ACP (Amorphous Calcium Phosphate)
What is it? Calcium Sodium-phosphosilicate

A synthetic mineral composed of calcium, sodium, phosphorous and silica, all elements naturally occurring in the body.

Silica (glass) containing Ca and PO is the driving mechanism that binds to the tooth surface.

Casein phosphopeptide and amorphous calcium phosphate (CPP-ACP)

Casein phosphopeptide is a milk protein peptide that is bound to amorphous calcium phosphate

The milk derived peptide containing amorphous Ca and PO is the driving mechanism that binds to the tooth surface.

Arginine bicarbonate and calcium carbonate

Arginine bicarbonate is an amino acid complex found in saliva that is bound to calcium carbonate

ACP

ACP is inorganic amorphous calcium phosphate, made by combining soluble salts of calcium and phosphorous

How does it work? NovaMin releases high levels of Ca2+ and P5+ into the oral environment, along with Na+ that increases oral pH, creating the ideal conditions for rapid tooth remineralization.

The silica containing Ca, PO and Na bind to the tooth surface.

The Na buffers the pH above 7 (the pH is needed to be above 7 to allow for the precipitation of crystals onto the tooth surface)

The NovaMin will release rapid and continuous deposition of a natural, crystalline hydroxyl-carbonate apatite (HCA) layer that is chemically and structurally the same as tooth mineral. No other man-made materials is known to directly lead to the formation of these crystals in the body. NovaMin has also been shown to have significant anti-microbial and anti-inflammatory benefits.

The milk derived peptide containing Ca and PO binds to natural plaque.

The amorphous calcium phosphate that is associated with the protein is released during acidic challenges.

Amorphous Ca and PO is highly soluble, the same continuous acidic attacks will rapidly wash the Ca and PO away.

The arginine complex binds to the tooth surface and allows the calcium carbonate to slowly dissolve and release calcium that is then available to remineralize the tooth surface. Two phase system containing calcium in one part and phosphate in another.

When the two salts are mixed, they rapidly form amorphous calcium phosphate that can precipitate onto the tooth surface then dissolve into the saliva to be available for tooth Remineralization.

Amorphous Ca and PO is highly soluble so continuous acidic attacks will rapidly wash the Ca and PO away.

What products contain this? SootheRx (OMNII Pharmaceuticals)

Dr. Collins Restore Toothpaste

Butler NuCare� Tooth Root Conditioner (Butler)

MI Paste (GC America)

Trident Gum (Cadbury Adams)

Proclude (Ortek)

Denclude (Ortek)

Arm & Hammer Enamel Care Toothpaste

Clinically Proven Benefits
  • Significant reduction of tooth sensitivity.
  • Remineralization of acid erosion and abrasion.
  • Inhibiting the development of dental caries.
  • Significant reduction of gingivitis.
  • Consumer noticeable whitening.
  • Remineralization of acid erosion.
  • Promotes fluoride uptake in plaque.
  • Significant reduction of tooth sensitivity.
  • Inhibiting the development of dental caries.
  • Improving tooth surface smoothness and gloss.
  • Remineralization of acid erosion and abrasion.
  • Removing extrinsic tooth stain.

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