DenClude™ Desensitizing Dental Cream

Home > Sensitive Teeth > Denclude

Why DenClude?

• Clinically proven to provide long-lasting relief of dental sensitivity in a 12 week stand-alone study.
• For Everyday home use by patients. Applied twice daily with a soft toothbrush or equivalent dental service.*
• Outstanding hygiene practice builder.
• Free of components found in popular tartar control and whitening toothpastes that may cause or contribute to the development of sensitive teeth.

*see package insert for additional information.

Denclude contains SensiStat, a breakthrough “super saliva” desensitizing complex that’s highly effective in immediately plugging and sealing open dentinal tubules.

SensiStat was developed and patented at a major U.S. dental school and is the fruit of over 30 years of research in saliva chemistry. The components of SensiStat–arginine (a saliva-based amino acid and key substrate responsible for alkali generation by bacterial plaque), calcium and bicarbonate/carbonate – work synergistically to form a unique complex that mimics saliva’s repair and protective properties.

The highly soluble arginine bicarbonate surrounds the particles of the poorly soluble calcium carbonate forming an alkaline paste-like complex. This “super saliva spackle” will immediately plug and seal off a tooth’s open dentinal tubules, thereby eliminating or reducing sensitive teeth.

For everyday home use by patients, applied twice daily with a soft toothbrush

DenClude Provides Relief For Sensitive Teeth; 40 Million Americans Can Now Relieve Their Pain

DenClude is a unique home treatment for the estimated 40 million Americans who suffer from sensitive teeth, a painful condition triggered by cold, sweet or acidic foods or beverages, breathing cold air, and touch by a metal object.

Tooth sensitivity can be increased by receding gums, which are caused by overly aggressive brushing, periodontal disease, and certain dental procedures including scaling and surgery. Tooth whitening and excessive use of anti-tarter toothpastes may also increase sensitivity. If left untreated, sensitive teeth can sometimes lead to serious dental problems, including pulp damage and tooth loss.

Applied twice daily with a toothbrush, DenClude seals and repairs open dentinal tubules, preventing the agonizing jabs of pain associated with sensitive teeth. Over-the-counter desensitizing toothpastes attempt to block the transmission of pain inside the tooth, without sealing the tubules. DenClude contains SensiStat, which was developed, clinically tested and patented by researchers at the School of Dental Medicine, Department of Oral Biology and Pathology, State University of New York at Stony Brook.

SensiStat was made available earlier in ProClude, the first commercially available desensitizing prophy paste, now used by thousands of dental professionals as part of routine, in-office, dental cleaning procedures. ProClude and DenClude were proven highly efficacious in separate clinical trials, and they should provide with immediate and sustained relief of sensitive teeth..

In a 12-week, 88-patient, double-blind clinical trial, DenClude reduced the pain of sensitive teeth by up to 60% when applied twice daily with a toothbrush. The study examined 826 teeth. Each subject in the trial had to have at least one tooth sensitive to either scratching with a dental explorer or to a one-second air blast or both. Sensitivity was determined at the initial screening visit and at 3, 8, and 12 weeks.

SensiStat is based on over 30 years of research in saliva chemistry and mimics saliva's repair and protective properties. It is comprised of arginine, a common amino acid found in saliva, along with bicarbonate and calcium carbonate. Together they form a natural "super saliva" complex that's highly effective in immediately plugging and sealing microscopic fluid-filled pores or tubules of the dentin.

The dentin is the portion of the tooth under the enamel that surrounds the nerve or pulp. The sensitive tooth process starts when gums recede thereby exposing the dentin to the mouth environment. When the exposed dentin comes in contact with cold, sweet or acidic foods or drinks, the fluid in the dentinal tubules can move and irritate nerve endings, causing acute pain.

Directions: Apply a thick ribbon of Denclude™ to a soft toothbrush or equivalent dental device. Brush thoroughly twice daily, especially at the gum line where most tooth sensitivity occurs. Expectorate after use. For best results, do not rinse, drink or eat for thirty minutes after application.

Precautions: As with all medications, keep out of reach of children. Store at room temperature.